Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol.

Anthony KongJames GoodAmanda KirkhamJoshua S SavageRhys MantLaura LlewellynJoanna ParishRachel SpruceMartin ForsterStefano SchipaniKevin HarringtonJoseph SaccoPatrick MurrayGary MiddletonChristina Yap Hisham Mehanna

Published in: BMJ open (2020)

ISRCTN76291951 and NCT03028766.

Keyphrases

phase iii
study protocol
phase ii
clinical trial
early stage
randomized controlled trial
locally advanced
radiation therapy
open label
radiation induced
chemotherapy induced