Sedentary lifestyle with increased risk of obesity in urban adult academic professionals: an epidemiological study in West Bengal, India.
Sunandini GhoshManabi PaulKousik Kumar MondalSandip BhattacharjeePritha BhattacharjeePublished in: Scientific reports (2023)
Ectopic fat deposition is more strongly associated with obesity-related health problems including type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), hypothyroidism, arthritis, etc. Our study aimed at identifying the cumulative role of several risk factors in developing obesity and the role of ectopic fat (visceral fat) in predicting cardiovascular disease risk in varied age groups among urban adult academic professionals in West Bengal. 650 adults (Male = 456; Female = 194) associated with the academic job (age 20-65 years) in urban West Bengal were randomly selected for anthropometric, blood biochemical, and questionnaire-based analyses. Body Mass Index and Visceral Fat% exhibited comparable association with all the other anthropometric parameters (e.g. Whole body Subcutaneous fat%: male-Linear Regression Comparison: F = 11.68; P < 0.001; female-F = 6.11; P < 0.01). Therefore, VF% acts as a risk factor alongside BMI in instances where BMI fails alone. The presence of T2DM, hypertension, and hypothyroidism in the case groups confirmed their obesity-associated longitudinal pattern of inheritance. Unhealthy diet pattern indicates improper liver function, vitamin D deficiency, and increased erythrocytic inflammation. An overall sedentary lifestyle with parental history of obesity was found to be significant in the longitudinal transmission of the disease.
Keyphrases
- weight loss
- insulin resistance
- metabolic syndrome
- adipose tissue
- cardiovascular disease
- weight gain
- type diabetes
- physical activity
- high fat diet induced
- risk factors
- glycemic control
- body mass index
- mental health
- public health
- oxidative stress
- cardiovascular risk factors
- fatty acid
- skeletal muscle
- rheumatoid arthritis
- blood pressure
- cross sectional
- mitochondrial dna
- depressive symptoms
- gene expression
- dna methylation
- climate change
- copy number
- risk assessment