Depressive symptoms and cerebral microvascular disease in adults with Type 1 diabetes mellitus.
Christopher M RyanJ F KarpT J OrchardTina CostacouH J AizensteinJ R JenningsCaterina RosanoPublished in: Diabetic medicine : a journal of the British Diabetic Association (2019)
These findings suggest a cerebrovascular origin for depressive symptoms in adults with Type 1 diabetes, perhaps triggered by hyperglycaemia. Future longitudinal studies should investigate whether targeting hyperglycaemia and physical inactivity alleviates depressive symptoms, possibly by slowing the development of cerebral microvascular disease, in people with Type 1 diabetes.