Monochasma Savatieri Aqueous Extract inhibits Human Breast Cancer Cell Line Migration and Adhesion Without Generating Toxicity.
Lin TanJuan Carlos Solís-SáinzPublished in: Anti-cancer agents in medicinal chemistry (2024)
M. savatieri possesses anti-cancer activity without exerting cytotoxicity on breast cancer cells. The extract exhibited anti-migratory and anti-adhesion effects on breast cancer cells by regulating Erk and Akt signaling pathways and the expression of caveolin-1. In addition, acteoside present in M. savatieri could be responsible for the observed effects.
Keyphrases
- breast cancer cells
- signaling pathway
- oxidative stress
- pi k akt
- endothelial cells
- cell proliferation
- poor prognosis
- biofilm formation
- induced apoptosis
- anti inflammatory
- epithelial mesenchymal transition
- induced pluripotent stem cells
- cell migration
- binding protein
- ionic liquid
- pluripotent stem cells
- escherichia coli
- staphylococcus aureus
- cystic fibrosis
- breast cancer risk
- endoplasmic reticulum stress