Vertebroplasty for osteoporotic vertebral fracture.
Christian RouxBernard CortetValérie BoussonThierry ThomasPublished in: RMD open (2021)
Appropriate care of patients with a recent painful osteoporotic vertebral fracture (VF) requires immobilisation, analgesics and spinal orthoses. Some VFs are however responsible for disabling pain and prolonged bed rest. In this context, vertebroplasty techniques have been proposed with a large benefit in case series and open-label randomised studies, but lack efficacy in three among four double-blind randomised studies. The objectives of the treatment of a recent painful VF are to relieve pain and to preserve mechanical conditions. With this in mind, we report an experts' opinion paper on the indications for vertebroplasty and research agenda for clinical studies.
Keyphrases
- open label
- bone mineral density
- clinical trial
- double blind
- placebo controlled
- pain management
- chronic pain
- phase iii
- phase ii
- study protocol
- postmenopausal women
- neuropathic pain
- phase ii study
- case control
- healthcare
- body composition
- spinal cord
- palliative care
- hip fracture
- randomized controlled trial
- radiation therapy
- global health
- spinal cord injury
- affordable care act