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Diagnostic and therapeutic biomarkers for Alzheimer's disease in human-derived platelets.

Jae-Woong MinJina LeeHui-Jin MunDae Hoon KimByeong-Gyu ParkBora YoonJin-Hyeob RyuHyun-Jeong Cho
Published in: Genes & genomics (2020)
We developed a novel AD diagnostic method using triple matching and miRNA-imbalance. The triple matching and miRNA imbalance-based relative ratio diagnosis method we developed will be very powerful in resolving the challenges of absolute diagnostic quantification based on biomarker expression. Also, our research results suggest the possibility of a treatment target for AD.
Keyphrases
  • endothelial cells
  • poor prognosis
  • cognitive decline
  • pluripotent stem cells
  • binding protein
  • combination therapy
  • red blood cell