Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains.
Tarin M BigleyMonica XiongMuhammad AliYun ChenChao WangJavier Remolina SerranoAbdallah EteleebOscar HarariLiping YangSwapneel J PatelCarlos CruchagaWayne M YokoyamaDavid M HoltzmanPublished in: Molecular neurodegeneration (2022)
Although MRV does infect the brain and cause transient neuroinflammation, our data do not support a role for murine or human roseoloviruses in the development of Aβ plaque formation and AD.