Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats.
Shuyue ChengJingjing XuWei WangRui WangHaonan LiZhijun JiangDexiang LiuFang PanPublished in: Psychopharmacology (2023)
mGluR5 was involved in IFS-induced PTSD-like behavior by changing BDNF, TrkB, and GLT-1 expression.