Upregulation of sodium taurocholate cotransporter polypeptide during hepatogenic differentiation of umbilical cord matrix mesenchymal stem cells facilitates hepatitis B entry.
Camillo SargiacomoHoda El-KehdyKai DallmeierJoery de KockClara Hernandez-KellyVera RogiersArturo OrtegaJohan NeytsEtienne SokalMustapha NajimiPublished in: Stem cell research & therapy (2017)
Altogether, our data support the usefulness of D-UCMSCs as a unique human and non-transformed in-vitro model to study the early stages of HBV infection thanks to its ability to endogenously regulate the expression of hNTCP.