Proximal Tubule Translational Profiling during Kidney Fibrosis Reveals Proinflammatory and Long Noncoding RNA Expression Patterns with Sexual Dimorphism.

Haojia WuChun-Fu LaiMonica Chang-PanessoBenjamin D Humphreys

Published in: Journal of the American Society of Nephrology : JASN (2019)

This comprehensive transcriptomic map of the proximal tubule revealed sexually dimorphic gene expression that may reflect sex-related disparities in CKD, proinflammatory gene modules, and previously unappreciated proximal tubule-specific bidirectional lncRNA regulation.

Keyphrases

long noncoding rna
gene expression
single cell
poor prognosis
chronic kidney disease
dna methylation
genome wide
rna seq
copy number
healthcare
binding protein
liver fibrosis
genome wide identification