Systematic Review of Platelet-Rich Plasma for Low Back Pain.
Edilson Silva MachadoFabiano Pasqualotto SoaresErnani Vianna de AbreuTaís Amara da Costa de SouzaRobert MevesHans GrohsMary A AmbachAnnu NavaniRenato Bevillaqua de CastroDaniel Humberto PozzaJosé Manuel Peixoto CaldasPublished in: Biomedicines (2023)
In this systematic review, we analyzed articles from English, Spanish and Russian language, from large databases and grey literature. PRP was in general an effective and safe treatment for degenerative LPB. Positive results were found in almost studies, a small number of adverse events were related, the risk of bias of the RCTs was low. Based on the evaluation of the included studies, we graded as level II the quality of the evidence supporting the use of PRP in LBP. Large-scale, multicenter RCTs are still needed to confirm these findings.