The interaction of 5-HTT variation, recent stress, and resilience on current anxiety levels in adolescents and young adults from the general population.

Theresa M OllmannCatharina VossJohn VenzEsther SeidlJana HoyerHanna KischeLars PieperMiriam A SchieleKatharina DomschkeKatja Beesdo-Baum

Published in: Depression and anxiety (2020)

Findings revealed an interactive relationship between 5-HTTLPR genotype and recent stress suggesting resilience to function as an additional dimension buffering the impact of a GxE risk constellation. Early interventions to build resilience may be useful to prevent an escalation of distress and associated unfavorable health outcomes.

Keyphrases

climate change
social support
depressive symptoms
randomized controlled trial
clinical trial
sleep quality
heat stress