Regulation of somatostatin expression by vitamin D3 and valproic acid in human adipose-derived mesenchymal stem cells.

Luise DoeringRahul KhatriSebastian Friedrich PetryHeinrich SauerHans-Peter HowaldtThomas Linn

Published in: Stem cell research & therapy (2019)

Human ADMSC carry the VDR. The vitamin D metabolising enzyme 25-Hydroxylase responded to the addition of vitamin D3. Moreover, our results demonstrate that somatostatin expression in ADMSC is constitutive, partially secreted and regulated by vitamin D3 and VPA.

Keyphrases

endothelial cells
poor prognosis
induced pluripotent stem cells
pluripotent stem cells
binding protein
adipose tissue
metabolic syndrome