Clinical Impact of Multiplex Molecular Diagnostic Testing in Children With Acute Gastroenteritis Presenting to an Emergency Department: A Multicenter Prospective Study.

Andrew T PaviaDaniel M CohenAmy L LeberJudy A DalyJami T Jackson Rangaraj Selvarangan Neena KanwarJeffrey M BenderJennifer Dien Bard Ara FestekjianSusan DuffyChari LarsenKristen M HolmbergTyler BardsleyBenjamin HaalandKevin M BourzacChristopher StockmannKimberle C Chapin Daniel T Leung

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)

Routine molecular multiplex testing for all children who presented to the ED with acute gastroenteritis detected more clinically relevant pathogens and led to a 21% decrease in return visits. Additional research is needed to define patients most likely to benefit from testing. Clinical Trials Registration. NCT02248285.

Keyphrases

emergency department
clinical trial
end stage renal disease
newly diagnosed
ejection fraction
high throughput
prognostic factors
single molecule
randomized controlled trial
real time pcr
respiratory failure
cross sectional
double blind
intensive care unit
case report
drug induced
phase ii
open label