Trajectory analyses to identify persistently low responders to COVID-19 vaccination in patients with inflammatory bowel disease: a prospective multicentre controlled study, J-COMBAT.
Kenji WatanabeMasanori NojimaHiroshi NakaseToshiyuki SatoMinoru MatsuuraNobuo AoyamaTaku KobayashiHirotake SakurabaMasakazu NishishitaKaoru YokoyamaMotohiro EsakiFumihito HiraiMasakazu NagahoriSohachi NanjoTeppei OmoriSatoshi TanidaYoshihiro YokoyamaKei MoriyaAtsuo MaemotoOsamu HandaNaoki OhmiyaKiichiro TsuchiyaShinichiro ShinzakiShingo KatoMasashi NamikawaHiroki TanakaNoritaka TakatsuAtsushi NishidaJunji UmenoMasanao NakamuraYoshiyuki MishimaMikihiro FujiyaKenji TsuchidaSakiko HiraokaMakoto OkabeTakahiko ToyonagaKatsuyoshi MatsuokaAkira AndohYoshio HirotaTadakazu Hisamatsunull nullPublished in: Journal of gastroenterology (2023)
Most IBD patients showed a sufficient immune response to COVID-19 vaccination regardless of clinical factors. Assessment of changes over time is essential to optimize COVID-19 vaccination, especially in persistently low responders.