Gastroenteropancreatic Neuroendocrine Neoplasms in Patients with Inflammatory Bowel Disease: An ECCO CONFER Multicentre Case Series.
Stefano FestaGiulia ZerboniLauranne A A P DerikxDavide Giuseppe RibaldoneGabriele DragoniChristianne BuskensEls Nieveen van DijkumDaniela PuglieseFrancesco PanzutoIwona Krela-KaźmierczakHilla Reiss MintzAriella Bar-Gil ShitritMarìa ChaparroJavier P GisbertUri KopylovNiels TeichElez VainerIris NagtegaalFrank HoentjenMaria Jose GarciaRafal FilipKalliopi FoteinogiannopoulouIoannis E KoutroubakisMarjorie ArgolloRoy L J van WanrooijHendrik LajaTriana LobatonMarie TruyensTamas MolnarEdoardo SavarinoAnnalisa AratariClaudio PapiIdan GorenPublished in: Journal of Crohn's & colitis (2021)
In the largest case series to date, prognosis of patients with GEP-NEN and IBD seems favorable. Incidental NEN diagnosis correlates with an earlier NEN stage and IBD-related therapies are probably independent of NEN stage and grade. The association of GEP-NEN location and the segment affected by IBD may suggest a possible role of inflammation in NEN tumourigenesis.