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Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells.

Yi-Hsin LiangKuo-Hsing ChenJia-Huei TsaiYung-Ming ChengChang-Cheng LeeChiu-Hwa KaoKuang-Yu ChanYeh-Ting ChenWen-Ling HsuKun-Huei Yeh
Published in: Journal of biomedical science (2021)
Our study provides a novel rationale for the addition of bortezomib, a proteasome inhibitor, into new immunotherapy combinations.
Keyphrases
  • endothelial cells
  • poor prognosis
  • cell proliferation
  • induced pluripotent stem cells
  • newly diagnosed
  • pluripotent stem cells