Social genomics, cognition, and well-being during the COVID-19 pandemic.
James R BatemanSudarshan KrishnamurthyEllen E QuillenChristian E WaughKiarri N KershawSamuel N LockhartTimothy M HughesTeresa E SeemanSteve W ColeSuzanne CraftPublished in: medRxiv : the preprint server for health sciences (2023)
Eudaimonic and hedonic well-being remain important correlates of molecular markers of stress, even in people with MCI. However, prodromal cognitive decline appears to moderate the significance of coping strategies as a correlate of CTRA gene expression. These results suggest that MCI can selectively alter biobehavioral interactions in ways that could potentially affect the rate of future cognitive decline and may serve as targets for future intervention efforts.