A feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients.

Daniel S MartinMargaret McNeilChris Brew-GravesHelder FilipeRonan O'DriscollJia Liu StevensRachel BurnishAndrew F CumpsteyNorman R WilliamsMichael G MythenMichael Pw Grocott

Published in: Journal of the Intensive Care Society (2021)

Whilst conservative oxygenation was a feasible and safe intervention which achieved clear group separation in oxygenation levels, the model used in this trial will require alterations to improve future participant recruitment rates in the UK.

Keyphrases

study protocol
randomized controlled trial
blood flow
intensive care unit
clinical trial
phase iii
acute respiratory distress syndrome
current status
cancer therapy
phase ii
liquid chromatography
cross sectional
open label
drug delivery
mesenchymal stem cells
cell therapy