Transcriptomic analysis of the human habenula in schizophrenia.
Ege A YalcinbasBukola AjanakuErik D NelsonRenee Garcia-FloresKelsey D MontgomeryJoshua M StolzJoshua WuHeena R DivechaAtharv ChandraRahul A BharadwajSvitlana V BachAnandita RajpurohitRan TaoJoo-Heon ShinJoel E KleinmanThomas M HydeDaniel R WeinbergerLouise A Huuki-MyersLeonardo Collado-TorresKristen R MaynardPublished in: bioRxiv : the preprint server for biology (2024)
These results identify topographically organized cell types with distinct molecular signatures in the human Hb. They further demonstrate unique transcriptomic changes in the epithalamus associated with schizophrenia, thereby providing molecular insights into the role of Hb in neuropsychiatric disorders.