The cerebrospinal fluid CD4/CD8 ratio and interleukin-6 and -10 levels in neurosarcoidosis: a multicenter, pragmatic, comparative study.

T ChazalM CostopoulosElisabeth MaillartC FleuryD PsimarasP LegendreM Pineton de ChambrunJ HarocheC LubetzkiZ AmouraM Legarff-TavernierFleur Cohen-Aubart

Published in: European journal of neurology (2019)

The CSF CD4/CD8 ratio and IL-6 concentration are increased in neurosarcoidosis compared to MS and other inflammatory disorders. A CSF IL-6 concentration >50 pg/ml is associated with relapse or progression of neurosarcoidosis. IL-10 levels may be elevated in neurosarcoidosis.

Keyphrases

cerebrospinal fluid
mass spectrometry
multiple sclerosis
ms ms
oxidative stress
clinical trial
cross sectional
randomized controlled trial