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Comparative analysis of cellular expression pattern of schizophrenia risk genes in human versus mouse cortex.

Hai-Long ZhangJia-Wen LongWei HanJiuzhou WangWeichen SongGuan Ning LinDong-Min Yin
Published in: Cell & bioscience (2019)
GABAergic neurons are more conserved in the expression of SRG than glutamatergic neurons while the non-neuronal cells show the species conservation for the expression of all SRG. It should be cautious to use mouse models to study those SRG which show different cellular expression pattern between human and mouse cortex.
Keyphrases
  • poor prognosis
  • endothelial cells
  • binding protein
  • spinal cord
  • mouse model
  • long non coding rna
  • bipolar disorder
  • gene expression
  • pluripotent stem cells
  • genome wide
  • cell cycle arrest
  • brain injury
  • cerebral ischemia