Role of Isolated Limb Perfusion in the Era of Targeted Therapies and Immunotherapy in Melanoma. A Systematic Review of The Literature.
Lourdes Sevilla-OrtegaLara Ferrándiz-PulidoNatalia Palazón-CarriónMaría Del Carmen Álamo de la GalaRubén de Toro-SalasJosé Garnacho-MonteroJosé Antonio Marcos-RodríguezAna Agudo MartínezOmar Araji-TilianiMaría Cinta Calvo-MorónJosé Miguel Barquero-ArocaAntonio Ramón Fernández-LópezJosé María Jaime-BorregoJuan Carlos Santos-JiménezDavid Moreno-RamírezLuis de la Cruz MerinoPublished in: Cancers (2021)
ILP is still an effective and safe procedure for selected patients with unresectable melanoma of the limbs. In the era of targeted therapies and immunotherapy, ILP remains an acceptable and reasonable palliative treatment alternative, especially to avoid limb amputations. The ongoing clinical trials combining systemic therapies and ILP will provide more valuable information in the future to clarify the potential synergism of both strategies.
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