Transcriptional changes after herpes simplex virus type 1 infection in human trabecular meshwork cells.
Jin A ChoiHyun-Hee JuJu-Eun KimSeon-Kyu KimDonghyun JeeJiyoung LeeChan Kee ParkSoon-Young PaikPublished in: PloS one (2019)
In human TM cells, HSV-1 induced transcriptional suppression of many components related to fibrosis and enhanced expression of both PDGF-BB and MCP-1. Our study may provide a novel mechanism for the pathogenesis of HSV-1 infection in TM cells.