Exploring the influence of baseline rheumatoid factor levels on TNF inhibitor retention rate in patients with rheumatoid arthritis: a multicentre and retrospective study.
Clementina López MedinaJerusalem Calvo-GutiérrezM Carmen Ábalos-AguileraFrancisco CepasChamaida Plasencia-RodriguezAna Martínez FeitoAlejandro BalsaRegina Faré-GarcíaAntoni Juan-MasVirginia Ruiz-EsquideLuis SainzCésar Díaz-TornéFrancisco Javier Godoy-NavarreteIsabel Añón-OñateNatalia Mena VázquezSara Manrique ArijaMarina Soledad Moreno-GarcíaRafaela Ortega-CastroAlejandro Escudero-ContrerasPublished in: RMD open (2024)
CZP showed a longer retention rate than mAB and ETA in patients with very high RF levels (≥200 IU/mL), while these differences were absent in patients with <200 IU/mL levels. The results suggest the potential effect of RF on binding the fragment crystallisable portion of certain TNFi.