Regulatory T cells and IgE expression in duodenal mucosa of Strongyloides stercoralis and human T lymphotropic virus type 1 co-infected patients.
Luis E Malpica-CastilloA Clinton WhiteCristina LeguiaNatalia FreundtNicolas BarrosCesar ChianE Antonio AntunezMartin MontesPublished in: PLoS neglected tropical diseases (2019)
Our data shows increased Treg cell numbers localized adjacent to the parasites in the duodenum SS/HTLV-1 patients. In addition, other T lymphocytes and IgE expressing cells were decreased adjacent to the parasites, suggesting an important role for Tregs in down-regulating local parasite effector responses.
Keyphrases
- regulatory t cells
- end stage renal disease
- dendritic cells
- plasmodium falciparum
- endothelial cells
- induced apoptosis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- poor prognosis
- prognostic factors
- single cell
- cell therapy
- cell cycle arrest
- peritoneal dialysis
- mesenchymal stem cells
- induced pluripotent stem cells
- machine learning
- endoplasmic reticulum stress
- long non coding rna
- binding protein
- patient reported
- pluripotent stem cells
- life cycle