In Vivo Molecular Profiling of Human Glioma : Cross-Sectional Observational Study Using Dynamic Susceptibility Contrast Magnetic Resonance Perfusion Imaging.
Johann-Martin HempelJens SchittenhelmUwe KloseBenjamin BenderGeorg BierMarco SkardellyGhazaleh TabatabaiSalvador Castaneda VegaUlrike ErnemannCornelia BrendlePublished in: Clinical neuroradiology (2018)
The DSC-MRI procedure may provide insight into the IDH1/2 mutation and ATRX expression status and MGMT methylation profile of diffuse glioma; however, taking integrated oligodendroglioma into account limits the diagnostic performance of rCBV in non-invasively predicting the molecular subtype.
Keyphrases
- contrast enhanced
- magnetic resonance
- cross sectional
- magnetic resonance imaging
- endothelial cells
- low grade
- poor prognosis
- high resolution
- computed tomography
- diffusion weighted imaging
- dna methylation
- genome wide
- minimally invasive
- single cell
- single molecule
- mass spectrometry
- gene expression
- high grade
- wild type
- long non coding rna