CRISPR/Cas9-mediated genome editing in Penicillium oxalicum and Trichoderma reesei using 5S rRNA promoter-driven guide RNAs.

Qi WangQinqin ZhaoQin LiuXin HeYaohua ZhongYuqi QinLiwei GaoGuodong LiuYinbo Qu

Published in: Biotechnology letters (2020)

Efficient genome editing systems were developed in filamentous fungi P. oxalicum and T. reesei by using heterologous or native 5S rRNA promoters for guide RNA expression.

Keyphrases

genome editing
crispr cas
poor prognosis
dna methylation
gene expression
transcription factor
binding protein
saccharomyces cerevisiae
nucleic acid