A high-volume, low-cost approach to participant screening and enrolment: Experiences from the T4DM diabetes prevention trial.

Karen BrackenAnthony KeechWendy HagueCarolyn AllanAnn ConwayMark DanielVal GebskiMathis GrossmannDavid J HandelsmanWarrick J InderAlicia JenkinsRobert McLachlanKristy P RobledoBronwyn StuckeyBu B YeapGary Wittert

Published in: Clinical trials (London, England) (2019)

A multi-step, semi-automated screening process with web-based pre-screening facilitated low-cost, high-volume participant enrolment to this large, multicentre randomised controlled trial. Centralisation and automation of screening activities resulted in substantial savings compared to previous, similar studies. Our screening approach could be adapted to other randomised controlled trial settings to minimise the cost of screening large numbers of participants.

Keyphrases

low cost
study protocol
clinical trial
type diabetes
cardiovascular disease
randomized controlled trial
machine learning
mental health
deep learning
adipose tissue
cross sectional