C ritical Care C yc ling to Improve L ower E xtremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ventilated patients.
Michelle E KhoJulie ReidAlexander J MolloyMargaret S HerridgeAndrew J SeelyJill C RudkowskiLisa BuckinghamDiane Heels-AnsdellTim KarachiAlison E Fox-RobichaudIan M BallKaren E A BurnsJoseph R PellizzariChristopher FarleySue BerneyAmy M PastvaBram RochwergFrédérick D'AragonFrancois LamontagneErick H DuanJennifer L Y TsangPatrick ArchambaultShane W EnglishJohn MuscedereKarim SerriJean-Eric TarrideSangeeta MehtaAvelino C VercelesBrenda ReeveHeather O'GradyLaurel KellyGeoff StrongAbby H HurdLehana ThabaneDeborah J Cooknull nullPublished in: BMJ open (2023)
NCT03471247 (Full RCT); NCT02377830 (CYCLE Vanguard 46 patient internal pilot).
Keyphrases
- clinical trial
- study protocol
- end stage renal disease
- double blind
- open label
- randomized controlled trial
- ejection fraction
- chronic kidney disease
- healthcare
- newly diagnosed
- palliative care
- intensive care unit
- prognostic factors
- peritoneal dialysis
- cross sectional
- quality improvement
- patient reported outcomes
- case report
- patient reported
- chronic pain
- acute respiratory distress syndrome