An optimized radiosynthesis of [18 F]FNDP, a positron emission tomography radiotracer for imaging soluble epoxide hydrolase (sEH).

Babak Behnam AzadDaniel P HoltHayden T Ravert Andrew G HortiRobert F Dannals

Published in: Journal of labelled compounds & radiopharmaceuticals (2018)

In this concise practitioner protocol, the radiochemical synthesis of [18 F]FNDP suitable for human positron emission tomography studies is described and the results from validation productions are presented. The high specific activity radiotracer product is prepared as a sterile, apyrogenic solution that conforms to current Good Manufacturing Practice requirements.

Keyphrases

positron emission tomography
pet imaging
computed tomography
endothelial cells
high resolution
pet ct
randomized controlled trial
healthcare
primary care
induced pluripotent stem cells
pluripotent stem cells
quality improvement
photodynamic therapy
solid state