Gene signature fingerprints stratify SLE patients in groups with similar biological disease profiles: a multicentre longitudinal study.
Mohamed Javad WahadatDieneke Schonenberg-MeinemaCornelia G van Helden-MeeuwsenSander J van TilburgNoortje GrootEllen J H SchatorjéEsther P A H HoppenreijsPetra C E Hissink MullerDanielle M C BrinkmanDenis DvorakMarleen VerkaaikJ Merlijn van den BergKateřina BouchalováSylvia KamphuisMarjan A VersnelPublished in: Rheumatology (Oxford, England) (2022)
The identified gene signatures were associated with disease activity and were indicated to be suitable tools for stratifying SLE patients into groups with similar activated immune pathways that may guide future treatment choices.
Keyphrases
- disease activity
- systemic lupus erythematosus
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- clinical trial
- prognostic factors
- rheumatoid arthritis patients
- randomized controlled trial
- copy number
- ankylosing spondylitis
- study protocol
- patient reported
- patient reported outcomes
- current status