Investigation of HPLF-111624 in Modified Experimental Models of Ulcerative Proctitis and Anal Fissure in Rats.

Mallappa OnkaramurthyMohammed Mukhram AzeemuddinMirza Rizwan BaigPavan Heggadadevanakote KendagannaMohamed RafiqUddagiri Venkanna Babu

Published in: Journal of experimental pharmacology (2022)

The results showed that the modified experimental models for UP and AF resemble the human pathological conditions and are simple, versatile and may be used for screening drugs intended for these conditions. Intervention with HPLF-111624 was found to be effective in improving the pathological state of UP and AF.

Keyphrases

atrial fibrillation
endothelial cells
randomized controlled trial
pluripotent stem cells
drug induced