Opioid-free anaesthesia with dexmedetomidine and lidocaine versus remifentanil-based anaesthesia in cardiac surgery: study protocol of a French randomised, multicentre and single-blinded OFACS trial.

Emmanuel BesnierMouhamed Djahoum MoussaCaroline ThillFlorian VallinNathalie DonnadieuSophie RuaultEmmanuel LorneVincent ScherrerJulien LanoiseléeThomas LefebvrePierre SentenacOsama Abou-Arab

Published in: BMJ open (2024)

NCT04940689, EudraCT 2020-002126-90.

Keyphrases

study protocol
cardiac surgery
randomized controlled trial
acute kidney injury
clinical trial
open label
placebo controlled
double blind
chronic pain
pain management
phase ii
cross sectional