Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years.

Jonathan GreenAndrew PicklesGreg PascoRachael BedfordMing Wai WanMayada ElsabbaghVicky SlonimsTeea GligaEmily J H JonesCeleste CheungTony CharmanMark Johnsonnull null

Published in: Journal of child psychology and psychiatry, and allied disciplines (2017)

Follow-up to 3 years of the first RCT of a very early social communication intervention for infants at familial risk of developing autism has shown a treatment effect, extending 24 months after intervention end, to reduce the overall severity of autism prodromal symptoms and enhance parent-child dyadic social communication over this period. We highlight the value of extended follow-up and repeat assessment for early intervention trials.

Keyphrases

randomized controlled trial
autism spectrum disorder
intellectual disability
mental health
healthcare
study protocol
early onset
cross sectional
clinical trial
adipose tissue
open label
weight loss