Multiple reaction monitoring (MRM)-profiling for biomarker discovery applied to human polycystic ovarian syndrome.
Fernanda Bertuccez CordeiroChristina Ramires FerreiraTiago Jose Paschoal SobreiraKaren E YannellAlan K JarmuschAgnaldo P CedenhoEdson G Lo TurcoRobert Graham CooksPublished in: Rapid communications in mass spectrometry : RCM (2018)
MRM-profiling is a supervised method characterized by its simplicity, speed and the absence of chromatographic separation. It can be used to rapidly isolate discriminating molecules in healthy/disease conditions by tailored screening of signals associated with hundreds of molecules in complex samples.