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Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats.

Shuyue ChengJingjing XuWei WangRui WangHaonan LiZhijun JiangDexiang LiuFang Pan
Published in: Psychopharmacology (2023)
mGluR5 was involved in IFS-induced PTSD-like behavior by changing BDNF, TrkB, and GLT-1 expression.
Keyphrases
  • prefrontal cortex
  • poor prognosis
  • posttraumatic stress disorder
  • social support
  • stress induced
  • binding protein
  • high glucose
  • mouse model
  • depressive symptoms
  • drug induced
  • cognitive impairment