Multicentre, randomised, open-label, phase IV-III study to evaluate the efficacy of cloxacillin plus fosfomycin versus cloxacillin alone in adult patients with methicillin-susceptible Staphylococcus aureus bacteraemia: study protocol for the SAFO trial.
Sara GrilloGuillermo CuervoJordi CarratalaRafael San-JuanJose M AguadoLaura MorataSilvia Gomez-ZorrillaJoaquín López-ContrerasOriol GaschAina Gomila-GrangeSimona IftimieGraciano Garcia-PardoEsther CalboLucía Boix-PalopIsabel OriolAlfredo Jover-SáenzLuis Eduardo López-CortésGorane EubaMalen AguirregabiriaMaria Jose Garcia-PaisFrancesca GioiaJose Ramón PañoMaria Luisa Pedro-BotetRosa Maria BenítezMaria Teresa Pérez-RodríguezYolanda MeijeMaria Belén Loeches-YagüeGertrudis HornaDamaris BerbelMaria Ángeles DomínguezAriadna PadullésSara CoboPilar HereuSebastian VidelaCristian TebeNatàlia PallarésJosep M MiroMiquel Pujolnull nullPublished in: BMJ open (2021)
The protocol has been approved by AEMPS with the Trial Registration Number EudraCT 2018-001207-37. ClinicalTrials.gov Identifier: NCT03959345; Pre-results.