Single agent efficacy of the HDAC inhibitor DATS in preclinical models of glioblastoma.

Arabinda DasFraser HendersonStephen LoweGerald C WallaceWilliam A VandergriftScott M LindhorstAbhay K VarmaLibby K InfingerPierre GiglioNarendra L BanikSunil J PatelDavid Cachia

Published in: Cancer chemotherapy and pharmacology (2018)

DATS may be an effective and well-tolerated therapeutic agent in preventing tumor progression and inducing apoptosis in human GB.

Keyphrases

endothelial cells
oxidative stress
endoplasmic reticulum stress
poor prognosis
induced pluripotent stem cells
cell cycle arrest
cell death
pluripotent stem cells
histone deacetylase
stem cells
long non coding rna