Evaluating the Effectiveness and Safety of Evinacumab in Treating Hypercholesterolemia and Hypertriglyceridemia: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Hussain Sohail RangwalaHareer FatimaMirha AliMuhammad Ashir ShafiqBurhanuddin Sohail RangwalaVikash VirwaniAashish KumarSyed Ali ArsalAdarsh RajaSandesh RajaMuhammad Saqlain MustafaPublished in: American journal of cardiovascular drugs : drugs, devices, and other interventions (2024)
High-dose evinacumab (15 mg) consistently demonstrated efficacy in reducing cholesterol and other lipid markers, with favorable tolerability. Further research is warranted to comprehensively assess its safety and clinical effectiveness, emphasizing the need for additional data to support its use in managing cardiovascular disease.
Keyphrases
- high dose
- cardiovascular disease
- systematic review
- low density lipoprotein
- randomized controlled trial
- low dose
- cardiovascular events
- open label
- stem cell transplantation
- electronic health record
- type diabetes
- big data
- fatty acid
- clinical trial
- cardiovascular risk factors
- metabolic syndrome
- coronary artery disease
- data analysis
- artificial intelligence
- placebo controlled