Erosion regression in patients with rheumatoid arthritis after upadacitinib-a pilot study using high resolution peripheral quantitative computed tomography.
Ho SoIsaac ChengVivian Wing-Yin HungQihan WuMartin LiVivian HungLing QinChun-Kwok WongLai Shan TamPublished in: Rheumatology (Oxford, England) (2024)
Despite a similar improvement in RA disease activity after upadacitinib compared with csDMARDs, a differential regression of erosion on HR-pQCT was observed in patients received upadacitinib. The potential role of JAK1 inhibition in erosion repair should be investigated.
Keyphrases
- disease activity
- rheumatoid arthritis
- high resolution
- systemic lupus erythematosus
- computed tomography
- end stage renal disease
- ankylosing spondylitis
- rheumatoid arthritis patients
- chronic kidney disease
- ejection fraction
- newly diagnosed
- juvenile idiopathic arthritis
- magnetic resonance imaging
- prognostic factors
- randomized controlled trial
- mass spectrometry
- positron emission tomography
- study protocol
- risk assessment
- human health
- climate change
- atomic force microscopy
- single molecule