Signaling of free fatty acid receptors 2 and 3 differs in colonic mucosa following selective agonism or coagonism by luminal propionate.

Iain R ToughSarah ForbesHelen M Cox

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)

We conclude that luminal propionate costimulates FFA2 and FFA3 pathways, reducing anion secretion and slowing colonic motility; FFA2 via PYY mediation and FFA3 signaling by activation of enteric sensory neurons.

Keyphrases

fatty acid
spinal cord
social support
pseudomonas aeruginosa
candida albicans