Inflammation-associated intramyocellular lipid alterations in human pancreatic cancer cachexia.

Min DengJianhua CaoGregory van der KroftDavid P J van DijkMerel R AberleAndrej GrgicUlf P NeumannGeorg WiltbergerBenjamin BalluffFrank G SchaapRon M A HeerenSteven W M Olde DaminkSander S Rensen

Published in: Journal of cachexia, sarcopenia and muscle (2024)

Intramyocellular lipid accumulation in patients with cachexia is associated with both local and systemic inflammation, and characterized by changes in defined lipid species such as glycerolipids and glycerophospholipids.

Keyphrases

endothelial cells
fatty acid
oxidative stress
induced pluripotent stem cells
pluripotent stem cells
genetic diversity