Study protocol of the FIRE-8 (AIO-KRK/YMO-0519) trial: a prospective, randomized, open-label, multicenter phase II trial investigating the efficacy of trifluridine/tipiracil plus panitumumab versus trifluridine/tipiracil plus bevacizumab as first-line treatment in patients with metastatic colorectal cancer.
G SommerhäuserA KurreckS StintzingV HeinemannL Fischer von WeikersthalT DechowF KaiserM KarthausI SchwanerM FuchsA KönigC RoderburgI HoyerM QuanteA KianiS FruehaufL MüllerA Reinacher-SchickT J EttrichA StahlerDominik Paul ModestPublished in: BMC cancer (2022)
EU Clinical Trials Register (EudraCT) 2019-004223-20 . Registered October 22, 2019, ClinicalTrials.gov NCT05007132 . Registered on August 12, 2021.