Defining CD4 T helper and T regulatory cell endotypes of progressive and remitting pulmonary sarcoidosis (BRITE): protocol for a US-based, multicentre, longitudinal observational bronchoscopy study.
Laura L KothLaura D HarmacekElizabeth K WhiteNicholas Kostandinos ArgerLinda PowersBrenda R WernerRoman E MagallonPineet GrewalBriana Q BarkesLi LiMay GillespieSarah E CollinsJessica CardenasEdward S ChenLisa A MaierSonia M LeachBrian P O'ConnorNabeel Y HamzehPublished in: BMJ open (2021)
The study protocol has been approved by the Institutional Review Boards at National Jewish Hospital (IRB# HS-3118), University of Iowa (IRB# 201801750), Johns Hopkins University (IRB# 00149513) and University of California, San Francisco (IRB# 17-23432). All participants will be required to provide written informed consent. Findings will be disseminated via journal publications, scientific conferences, patient advocacy group online content and social media platforms.
Keyphrases
- social media
- study protocol
- multiple sclerosis
- health information
- randomized controlled trial
- cross sectional
- clinical trial
- pulmonary hypertension
- healthcare
- single cell
- transcription factor
- disease activity
- case report
- emergency department
- quality improvement
- dendritic cells
- stem cells
- regulatory t cells
- systemic lupus erythematosus
- open label
- acute care
- immune response
- bone marrow