Unravelling relationships between obesity, diabetes, and factors related to somatosensory functioning in knee osteoarthritis patients.
Lotte MeertSophie VervullensChristiaan H W HeusdensRob J E M SmeetsMira MeeusMichel G C A M MertensPublished in: Clinical rheumatology (2024)
The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA. However, no significant correlations were found between BMI or HbA1c levels and pain-related outcomes. Future research should focus on longitudinal studies to elucidate the causal relationships and further explore the impact of metabolic factors on pain mechanisms in this patient population. Key Points • The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA.
Keyphrases
- knee osteoarthritis
- chronic pain
- type diabetes
- adipose tissue
- transcranial direct current stimulation
- pain management
- neuropathic pain
- end stage renal disease
- ejection fraction
- newly diagnosed
- insulin resistance
- metabolic syndrome
- total knee arthroplasty
- cardiovascular disease
- fatty acid
- case report
- body mass index
- weight gain
- cross sectional
- spinal cord injury
- current status
- spinal cord
- postoperative pain
- high fat diet induced