MiR-191-5p is upregulated in culture media of implanted human embryo on day fifth of development.

Ricardo Josué Acuña-GonzálezMercedes Olvera-ValenciaJorge Skiold López-CanalesJair Lozano-CuencaMauricio Osorio-CaballeroHéctor Flores-Herrera

Published in: Reproductive biology and endocrinology : RB&E (2021)

Regarding adequate in vitro embryo development, hsa-miR-191-5p could possibly represent a positive biomarker, while has-miR-24-1-5p may indicate poor prognosis. This former miRNA modulates IGF2BP-1 and IGF2R, associated with the implantation window. On the other hand, hsa-miR-24-1-5p may be related to a poor prognosis of human embryo development.

Keyphrases

poor prognosis
long non coding rna
endothelial cells
induced pluripotent stem cells
pluripotent stem cells
pregnancy outcomes
binding protein
signaling pathway