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Patient-perceived symptomatic benefits of olanzapine treatment for nausea and vomiting in patients with advanced cancer who received palliative care through consultation teams: a multicenter prospective observational study.

Isseki MaedaEriko SatomiDaisuke KiuchiKaoru NishijimaYoshinobu MatsudaAkihiro TokoroKeita TagamiYoshihisa MatsumotoAkemi NaitoTatsuya MoritaSatoru Iwasenull nullHiroyuki OtaniTakuya OdagiriHiroaki WatanabeMasanori MoriYosuke MatsudaHiroka NagaokaMeiko MayuzumiYoshiaki KanaiNobuhiro SakamotoKeisuke Ariyoshi
Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2021)
Short-term and relatively low-dose olanzapine treatment was effective for multifactorial N/V. Confirmatory studies with longer observation periods are needed to clarify the duration of the effect and adverse events.
Keyphrases
  • palliative care
  • advanced cancer
  • low dose
  • depressive symptoms
  • clinical trial
  • physical activity
  • social support
  • high dose
  • combination therapy
  • double blind