Systematic Review and Meta-Analysis on Hysterectomy by Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared to Laparoscopic Hysterectomy for Benign Indications.
Susanne HousmansNargis NooriSupuni KapurubandaraJan J A BosteelsLaura CattaniIbrahim AlkatoutJan DeprestJan BaekelandtPublished in: Journal of clinical medicine (2020)
(1) Objective: We aimed to report an update of the systematic review and meta-analysis by Baekelandt et al. (2016). (2) Method: We followed PRISMA guidelines to perform this systematic review. We searched MEDLINE, EMBASE, CENTRAL and additional sources and aimed to retrieve randomised controlled trials (RCTs), controlled clinical trials (CCTs) and prospective/retrospective cohort studies in human subjects that allowed direct comparison of vNOTES to laparoscopy. (3) Results: Our search yielded one RCT and five retrospective cohort trials. Pooled analysis of two subgroups showed that, compared to conventional laparoscopy, vNOTES is equally effective to successfully remove the uterus in individuals meeting the inclusion criteria. vNOTES had significantly lower values for operation time, length of stay and estimated blood loss. There was no significant difference in intra- and postoperative complications, readmission, pain scores at 24 h postoperative and change in hemoglobin (Hb) on day 1 postoperative.
Keyphrases
- robot assisted
- systematic review
- meta analyses
- clinical trial
- minimally invasive
- patients undergoing
- cross sectional
- endothelial cells
- chronic pain
- coronary artery bypass
- ultrasound guided
- pain management
- drinking water
- randomized controlled trial
- induced pluripotent stem cells
- neuropathic pain
- clinical practice
- phase iii
- surgical site infection
- red blood cell
- acute coronary syndrome
- endoscopic submucosal dissection
- clinical evaluation