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Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease.

Shahzad S KhanEbsy JaimonYu-En LinJonas M NikoloffFrancesca TonelliDario R AlessiSuzanne R Pfeffer
Published in: bioRxiv : the preprint server for biology (2024)
Cilia loss in Parkinson's disease decreases dopaminergic neuroprotection due to inability to sense Hedgehog signals.
Keyphrases
  • cerebral ischemia
  • blood brain barrier